Tiny Bombs in your Blood – The Complement System

Tiny Bombs in your Blood – The Complement System


One of the key players of our immune system is the complement system. An army of millions and trillions of tiny bombs, which work together in a complex and elegant dance to stop intruders in your body.

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55 Responses

  1. Kurzgesagt – In a Nutshell says:

    Our Complement System is super complex and fascinating and we can’t get enough of it – so we also made a poster and postcards with its core workings step by step.
    Get it here: http://shop.kurzgesagt.org

    • ICameHere JustToComment says:

      Question: Is the Complement System, like the rest of the immune system, liable to hijacking by a specialised pathogen?

    • Keylanos Lokj says:

      take THAT atheists. how can you still believe God didnt create all that beautiful complexity.

    • Ernest Gary says:

      Very interesting…more please;)

    • Man In Black says:

      Hey, I have a suggestion…. how about at the end, when you finished all parts about the immune system, you make a video about the whole thing, and maybe a poster , that could be useful for school use, since this topic, even thou important , is often skipped in biology classes and a video/movie and or a poster would make it a lot easier for teachers to teach it…. just saying… (if you need another reason to, you can sell more merch that way, and I’m sure students would catch onto your content more 😉 )

  2. David W says:

    Me: hey look a notification that Kurzgesagt uploaded. Awesome

    Kurzgesagt: did you know that you have transformers in your body

  3. Alex Gonzales says:

    “A beautiful example of how many mindless things can do smart things together.”
    >Any group assignment with my friends.

    • WithClass says:

      @Riccardo La Rosa Why? Just… why? You just gave the code for depression, why would you do such a thing?

    • Scientist Walter says:


    • Elektr0 Gaming says:

      “A beautiful example of how many mindless things and a single mindful thing can pretend they are doing smart things together”

    • tradehamforsyrup says:

      @Riccardo La Rosa Ohh, wait, I just realized what it means. It’s been a while since I’ve seen that number.

  4. Memolous maximus says:

    *youre covered in fly’s*
    Me : *runs*
    *They Turn Into wasps*
    Me : *AAAAAAAAH*

  5. hemant kumar says:

    Amazing video, I never thought how complex our immune system is.

  6. Trevor Lebert says:

    Its like invading a country the size of Russia but the population is entirely Africanized Bees

    • spim randsley says:

      @Keylanos Lokj None of it screams god, that’s simply the presupposition echoing in your head… what you could think of as self induced case of seeing what you already believed.

    • anything_goes says:

      Why are we doing this. You are all a collection of idiots. Shut up and go outside: your squabbling is wasting my emotional resources.

    • Shayaan Lindow says:

      So basically invading russia

    • OG JT says:

      @Floop Bloop God doesn’t encourage war

      The New Testament

  7. TJ Rivera says:

    Anti vaxxers: if the immune system is so good why isn’t there an immune system two?

    Kurzesagt: observe

  8. Pinochet says:

    Kurzgesagt’s “The Immune System”: The Anime

  9. Zuzierd and the everything channel says:

    No thank you for teaching us stuff we didn’t know about

  10. 天吉Mark says:

    Awww this video is *sponsored by YOU* !!!
    I’m not working yet, but i watched all the ads for Kurzgesagt 🙂

    • My name is Ozymandias says:

      ​@pyrointeam It’s another way around,” Kurzgesagt” take the English video to translate it and upload it to their German channel which started a year ago.

    • EL30bro says:

      @pyrointeam I’m german, so the “you” part is right for me anyway xD

    • pyrointeam says:

      @EL30bro Yes for me too as i am german too, but it was not directed specifically at us germans, as there is the german channel for us, but it seems to me you are just as nerdy as me and prefer to watch it in english… XD

    • Shayaan Lindow says:

      天吉Mark Only real nibbas visit the advertiser to give them even more money

  11. Monkeybednep says:

    Didn’t appreciate the thought of having thousands of flies turn into wasps on me.
    I need to speak to your manager

    *Karen Intensifies*

  12. Every Cell A Universe says:

    The complement system is vital against virus infections, which can be very difficult for the body to combat. Viruses get inside our cells, and they hijack the cellular machinery for their use, and in some cases can avoid detection by staying silent inside the cells. Interestingly, not all virus infections lead to bad outcomes.

    One particularly fascinating virus type are retroviruses, that can cut and paste their genome inside ours. We have lots of ancient, non-working retrovirus genomes inside our cells leftover from infections long gone. Retroviruses can cause devastating illnesses like AIDS, but in some cases we have used the integrated retrovirus genes for our own use. In fact, a retrovirus infection millions of years ago likely initiated the evolution of all placental mammals.

    Btw, I make videos on microbiology.

    • Saoirse del Tufo says:

      Keylanos Lokj well if god is more complex, how do you explain its creation?

    • Martí Fontrodona says:

      You, my friend, just got yourself a brand new subscriber

    • Loren Z says:

      @Keylanos Lokj Yeahhh, I’m pretty sure “god” is the nonsense masterkey answer that ancient people came up with to cover everything they didn’t understand. Which is fine if you’re coming from a place of utter ignorance about how the universe works. Coming from people in the modern world, it’s disingenuous.

    • Mikey says:

      I read once that almost half of our entire genome is viral

    • Chloroplast ✔ says:


  13. Seraphim227 says:

    “Imagine a trillion bombs under your skin.”


  14. JohnVanilla says:

    “Imagine being covered in wasps”
    Beekeeper: Am i a joke to you?

  15. Anonymus Entity says:

    I would love to see a kurzgesagt science textbook with this art style. Perhaps on biology or physics.

  16. Susse Kind says:

    I fancy myself an amateur biology nerd. However, this is something I’m hearing about for the 1st time.
    I guess I got some research to do now.
    Thank you for the information.

  17. Kyle Dilbert says:

    “Imagine you are covered in thousands of flies”


    “Now imagine them turning into wasps”

    oooh no thank you!

  18. yes sir says:

    This was so incredibly interesting, what the hell. I’m trying to enjoy my summer, now want to learn about the immune system(though that’s what i’m going to be doing now). Excellent video!

  19. Fox Gamer says:

    Ayyy! More immune system episodes! Anymore, and we’ll have an episode “epidemic” on our hands. XD

  20. Marcus Byrd says:

    Kurzgesagt: “Imagine being covered in flies”
    Me: “No”
    Kurzgesagt: “Do it again”
    Me: “Stop”
    Kurzgesagt: “W A S P S”

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